Table 6. Minimal Critical Region in the two groups of patients.

MCR (localization by aCGH)	Patients	Size (Mb)	Possible genes
t-AML
−1q44 <241.94–247.19>	t-2, t-13	5.25	>25 genes among them SMYD3
−3p14.1p12.3 <69.67–79.19>	t-5, t-17	9.52	MITF FOXP1 EIF4E3 GRP27 PROK2 RYBP
			SHQ1 PPP4R2 PDZRN3 CNTN3 FAM86D
			FRG2C ZNF717 ROBO2 ROBO1
−5q31.3q33.1 <142.91–148.19>	t-1, t-2, t-4, t-5	5.28	ADRB2 DPYSL3 HTR44 POU4F3 PPP2R2B
			SPINK1 JAKMIP2 TCERG1 SPINK5 LARS
			RBM27 KCTD16 HMHB1 FBXO38 YIPF5
			SPINK7SCGB3A2 GPR151 PRELID2
			SH3RF2 PLAC8L1 STK32A SPINK6 SPINK9
+6q27<168.12–168.32>[1.50]	t-9, t-17	0.20	KIF25 FRMD1 HGC 6.1.1
−7p22.2 <3.02–3.12>	t-5, t-6, t-7, t-9, t-10	0.10	GNA12 CARD11
+7p15.2 <27,15–27,18>	t-14, t-16, t-17, t-19	0,03	HOXA6 HOXA7 HOXA9 HOXA10 miR-196b
−7q21.3 <97.69–101.88>	t-2, t-5, t-6, t-7, t-9,	4.19	NPTX2 LMTK2 BRI3 BAIAP2L1 BHLHB8 CUX1
	t-10		miR-86 miR-93miR-106b miR-548o
−7q33q34<135.74–137.48>	t-2, t-5, t-6, t-7, t-8, t-9	1.74	CHMR2 PTN DGK1 CREB3L2 miR-490
+8q24.3 <143.73–143.9>	t-3, t-14	0.17	PSCA LY6D JRK C8orf55 LY6K
			SLURP1 LYNX1 LYPD2
−12p13.2p13.1<11.82–13.33>	t-2, t-4, t-5	1.51	ETV6 CDKN1B CREBL2 EMP1 GPR19 LRP6
			GPRC5A HEBP1DDX47 MANSC1 GPRC5D
			KIAA1467 BCL2L14 DUSP16 APOLD1 GSG1
			HTR7P miR-613 miR-614 miR1244
+17q21.3 <22.80–78.65>	t-15, t-24	55.85	Whole 17q
−21q22.1 <35.11–35.15>	t-7, t-8, t-11, t-29	0.04	RUNX1
p-AML
+1q21q22<153.19–154.64>	p-23, p-24	1.4	>25 genes EFNA4 R1AP1 DPM3
			YY1AP1 DAP3 ROBLD3 CCT3 CLK2
+1q32.1q44<201.31–247.19>	p-6, p-23	45.69	Numerous genes
−3p21.3<44.20–49.02>	p-21, p-24, p-32	5.18	>40 genes SMARCC1 NCKIPSD
−7q31.2q36.3<115.49–158.78>	p-1 and p-2, p-7	43.29	Numerous genes
−9q22.3q31.1<93.92–103.96>	p-18, p-21	9.81	>60genes FANCC XPA
Amp 21q21.1<14.29–17.97> [5.46]	p-4, p-21	3.78	LIPI ABCC13 RBM11 HSPA13 SAMSN1
			NRIP1 USP25 C21orf34 CXADR BTG3
			miR-99a miR-125b-2hsa-let-7c
Amp 21q22.2<38.27–43.54> [3 & 5.2]	p-4, p-21, p-24	5,25	DSCR4 KCNJ15 ERG ETS2 BRWD1
			other genes
+21q22.3qter<43.54–46.91>	p-4, p-21, p-24	7.49	>50 genes

Column 1, the location of the MCR that follows the rules of tables 4 and 5; the figures in brackets and in bold are the ratios of the amplified regions. Column 2, patients; the figures in bold indicate the smaller CNA.