Skip to main content
. 2011 Feb 14;6(2):e17042. doi: 10.1371/journal.pone.0017042

Figure 3. Comparison of reaction kinetics with BSWA and bacterial alginate.

Figure 3

The specific activities of WT-his (white bars) and A53C-his-PEG (black bars) were determined with a model alginate substrate (BSWA) as well as with purified bacterial alginate (FRD1). The two enzymes are equally active with BSWA at saturating concentrations, but the PEGylated variant exhibits 80% faster kinetics with the bacterial substrate (p<0.01), which is the ultimate therapeutic target. Error bars represent standard deviation.