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. 2011 Feb 14;6(2):e17097. doi: 10.1371/journal.pone.0017097

Figure 3. Expression of the D-CblL-Δ70Z mutant reduces endocytosis of Grk-receptor in follicle cells.

Figure 3

(A and A′) The HRP signals represented the ligand-receptor complex in the follicle cell (green), and were detected in the dorsal-anterior corner of the middle stage egg chambers (arrowhead). (B, B′ and B″) Over-expression of D-CblL (red) promoted endocytosis of the ligand-receptor in follicle cells (arrows). (C, C′ and C″) However, expression of D-CblL-Δ70Z (red) significantly reduced HRP-Grk signals in the follicle cells. (B′ and C′) The D-CblL or D-CblL-Δ70Z expression are shown in B′ and C′, respectively. The composite image of several confocal sections of an egg chamber with HRP-Grk. Scale bars: 20 µm.