Table 5. Effect of IPTc on mean haemoglobin/haematocrit concentrations in intervention and control arms at the end of the intervention period.
Study Site | Drug Regimen | No. children | Mean Hb (g/dL)/Hct (%) concentration [95% CI] | p-value (z-test) | |
Kweku (2008) [22] | Hohoe | SP bimonthly | 550 | 9.2 (6.6–11.8) | 0.20 |
AS+AQ bimonthly | 464 | 9.2 (6.6–11.8) | 0.23 | ||
AS+AQ monthly | 559 | 9.4 (7.0–11.8) | 0.18 | ||
Placebo | 589 | 9.3 (6.7–11.9) | - | ||
Dicko (2008) [21] | Kambila | SP bimonthly | 55 | 32.1 (31.2–33.0) | 0.80 |
Control | 54 | 31.9 (31.0–32.8) | - | ||
Dicko (2011) [12] | Kati Region | SP+AQ | 1422 | 11.0 (10.7–11.2) | 0.06 |
Placebo | 1433 | 10.7 (10.5–10.9) | - | ||
Konaté (2011) [13] | Boussé | SP+AQ | 1444 | 11.0 (10.9–11.1) | <0.001 |
Placebo | 1441 | 10.4 (10.3–10.4) | - | ||
Sesay (2011) [23] | Farafenni | SP+AQ | 513 | 10.2 (7.1–13.3) | 0.79 |
Placebo | 533 | 10.3 (7.4–13.2) | - |
AQ: amodiaquine, AS: artesunate, CI: confidence interval, DHA: dihydroartemisinin, Hb: haemoglobin, Hct: haematocrit, PQ: piperaquine, SP: sulphadoxine pyrimethamine.