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. 2011 Feb 14;6(2):e17075. doi: 10.1371/journal.pone.0017075

Figure 9. Phase portrait of birhythmicity for Model 3.

Figure 9

Simulation of the two oscillatory regimes in the phase space for Model 3. The dashed lines represent the thresholds KMc, KMn and K for P, KP for Mn. The parameter values are the same as for Figure 6 (KMn = 0.1 nM) except KMc = 0.4 nM, K = 0.05 nM, KP = 2 nM, dP = 3 h−1, Mc11 = Mc21 = Mc12 = 0, Mc22 = 5 nM, Mc13 = 9 nM, Mc23 = 11.3 nM, Mc14 =  Mc24 = 25 nM. Note that, since the degradation constants dMn and dP have the same values, the trajectories in each domain are straight lines.