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. 2011 Jan 31;4:1. doi: 10.1186/1756-8935-4-1

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Copyright ©2011 Woodfine et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of 23 differentially methylated region (DMR) assays in 50 individual blood samples. (a) Average methylation levels of 50 different individuals. Red = maternal germ-line DMRs; pink = maternal somatic DMRs; dark blue = paternal germ-line DMRs; light blue = paternal somatic DMRs. Box plots show the median, inter-quartile range and maximum/minimum methylation B standard deviation of all C-phosphate guanines (CpGs) assayed for maternal and paternal DMRs. A significant difference was observed between the intra-assay variability reported (matched pair t-test, P = 0.007).