Table 4.
Most abundant biological process GO annotations of nucleolar-associated proteins with reliability index above 10
| Biological process GO term | Protein counta |
|---|---|
| Nucleolar-Enriched | |
| RNA metabolic process (GO:0016070) | 163 |
| of which rRNA processing (GO:0006364) | 35 |
| tRNA processing (GO:0008033) | 27 |
| Transcription, DNA-dependent (GO:0006351) | 35 |
| Cellular component organization (GO:0016043) | 81 |
| Ribosome biogenesis (GO:0042254) | 50 |
| of which rRNA processing (GO:0006364) | 35 |
| Regulation of biological process (GO:0050789) | 45 |
| Nucleoplasmic-nucleolar | |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139) | 118 |
| of which DNA repair (GO:0006281) | 52 |
| DNA replication (GO:0006260) | 43 |
| Regulation of biological process (GO:0050789) | 107 |
| of which Regulation of transcription, DNA-dependent (GO:0006355) | 35 |
| Signal transduction (GO:0007165) | 36 |
| Cellular component organization (GO:0016043) | 92 |
| of which Chromosome organisation (GO:0051276) | 68 |
| Cell cycle (GO:0007049) | 89 |
| Multicellular organismal development (GO:0007275) | 40 |
| Cell proliferation (GO:0008283) | 39 |
| Cell death (GO:0008219) | 27 |
| Nucleolar-cytoplasmic | |
| Protein metabolic process (GO:0019538) | 127 |
| of which Translation (GO:0006412) | 106 |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139) | 33 |
| Regulation of biological process (GO:0050789) | 27 |
| of which Signal transduction (GO:0007165) | 10 |
| Cellular component organisation (GO:0016043) | 18 |
| of which Organelle organisation (GO:0006996) | 11 |
a count includes proteins annotated with child terms