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PICK1 knockout (KO) preserves acute pain. A, Baseline paw withdrawal frequencies in response to various forces of von Frey monofilaments in naïve wild-type (WT) and PICK1 KO mice. B, Baseline paw withdrawal latencies in response to heat stimulation in naïve WT and PICK1 KO mice. C, Baseline tail-flick latencies in response to heat stimulation in naïve WT and PICK1 KO mice.
