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. 2011 Feb 3;7:11. doi: 10.1186/1744-8069-7-11

Figure 8.

Figure 8

L5 spinal nerve ligation (SNL) does not induce GluR2 internalization in dorsal horns from wild-type (WT) mice. A, GluR2 levels in the cytosolic fraction from the ipsilateral dorsal horns of WT and PICK1 knockout (KO) mice at different time points after L5 SNL. Top: Representative Western blots. Bottom: Statistical summary of the densitometric analysis expressed relative to naïve (0) mice after normalization to corresponding β-actin. B, GluR2 levels in the synaptosomal membrane fraction from the ipsilateral dorsal horn of WT and PICK1 KO mice at different time points after L5 SNL. Top: Representative Western blots. Bottom: Statistical summary of the densitometric analysis expressed relative to naïve (0) mice after normalization to corresponding N-cadherin.