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Schema of T cell activation and the inhibitory action of abatacept on costimulation. Copyright © 2008. Dove Medical Press. Reprinted with permission. Kuemmerle-Deschner JB, Benseler S. Abatacept in difficult-to-treat JIA.Biologics. 2008;2(4):865–874.31
Abbreviations: APC, antigen presenting cell; MHC, major histocompatibility complex; TCR, T cell receptor.
