Table 1.
Group | Sensitization | Allergen challenge | Treatment | Early phase n | Late phase n |
---|---|---|---|---|---|
1 | – | – | No treatment (NS/NC) | 8 | 8 |
2 | + | + | No treatment (S/C) | 8 | 8 |
3 | + | + | Alcaftadine vehicle | 8 | 8 |
4 | + | + | Olopatadine 0.1% | 8 | 8 |
5 | + | + | alcaftadine 0.25% | 8 | 8 |
Abbreviations: NS/NC, no sensitization, no challenge (naïve animals); S/C, sensitized, challenged.