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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Eur J Neurosci. 2010 Dec 29;33(4):736–747. doi: 10.1111/j.1460-9568.2010.07553.x

Figure 2. Motivation shifts: LY341495 in NAc shell suppresses appetitive eating and drinking but stimulates fearful motivated behavior.

Figure 2

Sagittal and horizontal maps of appetitive eating (A) and defensive treading (B) behavior generated by LY341495 mglu2/3 antagonism. Changes in the cumulative duration of eating behavior is shown as percentage of vehicle, while defensive treading behavior is shown as unit change from vehicle (given near zero levels of treading baseline). LY341495 microinjections in medial shell suppressed appetitive eating and enhanced defensive behavior throughout medial NAc shell. Histograms bars below and to the sides of the maps show mean values (error bars = SEM) for each behavior at rostrocaudal, dorsoventral and mediolateral levels.