Table 5. IgG reactivity towards the fetal brain in mothers, n (%).
The incidence of IgG specific towards various molecular weight proteins is represented as: total number with band (percentage of group with band). The average total number of IgG targets in the fetal brain was higher in mothers of AU and ASD children compared to mothers of TD children (mothers of ASD=1.63, mothers of AU=1.6, mothers of TD=1.15)
| Maternal IgG Targets in Fetal Brain | P values | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mothers of ASD n=65 |
Mothers of AU n=194 |
Mothers of ASD+AU n=259 |
Mothers of TD n=180 |
ASD vs TD |
AU vs TD |
AU+ASD vs TD |
AU vs ASD |
||
| Fetal Brain Protein (KDa) | 37 and 73 | 3 (4.6%) | 21 (10.8%) | 24 (9.3%) | 0 (0%) | 0.018 | <0.0001 | <0.0001 | NS |
| 37 (no 73) | 9 (13.8%) | 8 (4.2%) | 17 (6.6%) | 11 (6.1%) | NS (0.0643) |
NS | NS | 0.016 | |
| 39 and 73 | 8 (12.3%) | 15 (7.7%) | 23 (8.9%) | 3 (1.7%) | 0.001 | 0.0069 | 0.0015 | NS | |
| 39 (no 73) | 8 (12.3%) | 19 (9.8%) | 27 (10.4%) | 29 (16.1%) | NS | NS (0.088) |
NS (0.083) |
NS | |
| 73 (no 37or 39) | 6 (9.2%) | 36 (18.6%) | 42 (16.2%) | 22 (12.2%) | NS | NS | NS | NS (0.083) |
|