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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Virology. 2011 Jan 12;411(1):32–40. doi: 10.1016/j.virol.2010.12.029

Fig. 2. CCR5 mAb2D7 inhibits MVCres HIV-1 infection of JC6 cells more potently in the presence than in the absence of MVC.

Fig. 2

JC6 cells were incubated with and without 10 μM MVC for 1 h, followed by incubation with serial dilutions of CCR5 antibodies 2D7 (a), 45523 (b) or ROAb14 (c) for an additional hour, and then infected with HIV-1 pseudovirus bearing the indicated Env. Infectivity was determined by measuring luciferase activity on day 3, and data normalized to infectivity in the absence of mAb. Data points are mean ± S.D. of at least 2 replicates and are from one representative experiment of four (2D7), two (45523) and three (ROAb14).