Figure 2. SST Transcript Inverse Correlation with Age is reduced in females and in MDD.
mRNA signal and trendline are shown for control subjects (circles) in black, and in red for controls (triangles). A) In the male/female combined group, SST expression is significantly inversely correlated with age in control subjects (R=−0.357; p=0.005), but not in MDD subjects (R=−0.104; p=0.234). B) In the male cohort SST expression is significantly inversely correlated with age (R=−0.509, p=0.004), but not in MDD subjects (R=−0.143; p=0.243). C) In the female cohort, SST expression is inversely correlated with age at the trend level in control subjects (R=−0.278; p=0.089), and not in MDD subjects (R=−0.116; p=0.291).