Table 10.
Correlations Between Age of Menarche and Basal Pain Sensitivity and Analgesic Responses
| NOC Women | OC Women | |||
|---|---|---|---|---|
| Follicular Phase | Luteal Phase | Follicular Phase | Luteal Phase | |
| Basal Pain Responses | ||||
| Heat | 0.375 (0.049) | 0.427 (0.023) | −0.169 (0.331) | −0.116 (0.509) |
| Pressure | 0.187 (0.341) | 0.190 (0.333) | −0.002 (0.673) | −0.168 (0.341) |
| Ischemic | 0.113 (0.566) | 0.099 (0.617) | −0.199 (0.253) | −0.086 (0.623) |
| Morphine Analgesia | ||||
| Heat | −0.552 (0.041) | −0.437 (0.092) | 0.040 (0.876) | 0.536 (0.027) |
| Pressure | −0.129 (0.660) | 0.438 (0.117) | 0.522 (0.025) | 0.321 (0.210) |
| Ischemic | 0.774 (0.001) | 0.733 (0.003) | 0.158 (0.531) | −0.042 (0.872) |
| Pentazocine Analgesia | ||||
| Heat | 0.559 (0.038) | 0.277 (0.338) | −0.171 (0.511) | −0.331 (0.194) |
| Pressure | 0.324 (0.259) | 0.128 (0.663) | −0.550 (0.022) | −0.260 (0.314) |
| Ischemic | 0.187 (0.522) | 0.136 (0.642) | −0.126 (0.629) | −0.278 (0.280) |
For NOC women during the follicular phase, later age of menarche was associated with lower heat sensitivity, greater morphine analgesia on ischemic pain but reduced morphine analgesia for heat pain. Also, later menarche predicted greater pentazocine analgesia for heat pain. During the luteal phase, later menarche was associated with lower heat pain sensitivity and predicted greater morphine analgesia for ischemic pain among NOC women. For OC women during the follicular phase, later menarche was related to greater morphine analgesia on pressure pain but lower pentazocine analgesia tested against pressure pain. During the luteal phase in OC women, later menarche was correlated with greater morphine analgesia for heat pain. In bold significant p<0.05.