. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: Pain. 2011 Jan 15;152(3):614–622. doi: 10.1016/j.pain.2010.11.033

Table 7.

Correlations Between Morphine Analgesic Z-Scores and Hormone Levels, r (p)

	NOC Women (n = 14)			OC Women (n = 18)
	Heat pain	Ischemic pain	Pressure pain	Heat pain	Ischemic pain	Pressure pain
Follicular Estradiol	−0.32 (.260)	−0.06 (.848)	0.78 (.001)	−0.02 (.937)	−0.69 (.002)	−0.09 (.718)
Follicular Testosterone	−0.02(.951)	−0.17 (.573)	−0.131 (.657)	0.26(.294)	0.01 (.961)	0.51 (.030)
Follicular Progesterone	0.05 (.870)	−0.52 (0.058)	−0.20 (.499)	N/A	N/A	N/A
Luteal Estradiol	−0.122 (.677)	−0.13 (0.650)	−0.31 (.287)	0.16 (0.543)	−0.41 (.105)	0.09 (.739)
Luteal Testosterone	−0.62 (.017)	−0.12 (0.672)	0.04 (.886)	−0.08 (0.766)	0.02 (.960)	−0.42 (.091)
Luteal Progesterone	−0.21 (.464)	0.03 (0.928)	−0.40 (.151)	N/A	N/A	N/A

For NOC women higher follicular E2 levels were associated with greater morphine analgesia on pressure pain assays, and higher luteal testosterone predicted lower morphine analgesia for heat pain. For OC women, follicular E2 was associated with lower morphine on ischemic pain and follicular testosterone was associated with greater morphine analgesia on pressure pain. In bold significant p<0.05. Higher scores reflect higher analgesia.