TABLE 4.
Functional annotation analysis for female PTSD+ versus control participants
| Functional Term | q-value | Genbank | Fold | Symbol |
|---|---|---|---|---|
| Immune system process | 0.0054 | |||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_000206 | 1.53 | IL2RG | ||
| NM_001700 | 1.50 | AZU1 | ||
| NM_006435 | −1.51 | IFITM2 | ||
| NM_000057 | −1.63 | BLM | ||
| NM_006332 | −1.77 | IFI30 | ||
| Regulation of phagocytosis | 0.0104 | |||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_001700 | 1.50 | AZU1 | ||
| Leukocyte activation | 0.0197 | |||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_001700 | 1.50 | AZU1 | ||
| NM_000057 | −1.63 | BLM | ||
| Inflammatory response | 0.0383 | |||
| NM_000607 | 2.72 | ORM1 | ||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_001700 | 1.50 | AZU1 | ||
| Proteolysis | 0.0484 | |||
| NM_004851 | 2.22 | NAPSA | ||
| NM_014224 | 2.20 | PGA5 | ||
| NM_001700 | 1.50 | AZU1 | ||
| NM_019029 | −1.55 | CPVL | ||
| Immune response | 0.0701 | |||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_000206 | 1.53 | IL2RG | ||
| NM_006435 | −1.51 | IFITM2 | ||
| NM_006332 | −1.77 | IFI30 | ||
| Response to stimulus | 0.0809 | |||
| NM_000607 | 2.72 | ORM1 | ||
| NM_000660 | 1.54 | TGFB1 | ||
| NM_000206 | 1.53 | IL2RG | ||
| NM_001700 | 1.50 | AZU1 | ||
| NM_006435 | −1.51 | IFITM2 | ||
| NM_000057 | −1.63 | BLM | ||
| NM_006332 | −1.77 | IFI30 | ||
| Response to stress | 0.0980 | |||
| M_000607 | 2.72 | ORM1 | ||
| NM_000660 | 1.54 | TGFB1 | ||
| M_001700 | 1.50 | AZU1 | ||
| M_000057 | −1.63 | BLM |
Genes shown are significantly expressed for PTSD versus control with Student’s t-test p<0.05. The q-value is the probability that a random subset of genes drawn from the total set of genes will have one or more genes containing the functional term. For each functional term, it reflects the enrichment in frequency of that term in the input gene list relative to the entire genes of the term.