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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2011 Jan 9;17(3):309–318. doi: 10.1016/j.bbmt.2010.12.710

Fig. 6. Expansion and stability of Tregs in the recipients after allogeneic BMT.

Fig. 6

Experimental setting is the same as described in figure 5. One additional group of recipients was transferred with 0.5 × 106/mouse nTregs isolated from naïve B6 foxp3/gfp KI mice (Ly5.2+Ly5.1). A, percentages of Thy1.1+Ly5.1 (iTregs) or Ly5.2+Ly5.1 cells (nTregs) on gated CD4+ live cells in recipient spleen. B, absolute numbers of iTregs or nTregs are shown. C, absolute numbers of IFNγ+ iTregs or nTregs are presented per spleen. D, GFP expression on gated iTregs or nTregs in recipient spleen. E, percentages of GFP+ cells among gated iTregs or nTregs are shown in average ± 1 SD. Each group includes 3 or 4 mice, and the data represent 1 of 3 replicate experiments.