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Study Groups
| Groups | Number of animals studied radiographically | Number of animals imaged with micro PET & micro CT (imaging subgroup) | Number of animals studied histologically |
|---|---|---|---|
| Untreated control (C4 2b alone) | 10 | 5 | 10 |
| EV control (C4 2b+Empty vector) | 5 | 5 | 5 |
| RANK-Fc treatment (C4 2b+RANK-Fc) | 10 | 5 | 10 |
| RN treatment (C4 2b+RN [retronoggin]) | 10 | 5 | 10 |
| RN+RANK-Fc treatment (Combined treatment group; C42b+RN+RANK-Fc) | 10 | 5 | 10 |
