Skip to main content
. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Toxicology. 2011 Jan 13;281(1-3):37–47. doi: 10.1016/j.tox.2011.01.001

Fig. 5.

Fig. 5

MnTBAP does not protect the TrxR/Trx system from Cr(VI) exposure. BEAS-2B cells were pre-treated with 0.2 mM MnTBAP or vehicle for 2 hr and then Cr(VI) was added at the indicated concentrations for 3 hr. The cells were analyzed for TrxR specific activity (A), or by redox western blots for Trx1 (B) Prx1 (C), or Trx2. Data are the mean ± S.D. for independent experiments (n = 4 for TrxR activity except n = 3 for 25 µM; n = 5 for Trx1; n = 3 for Prx1 and Trx2). For all assays, two-way ANOVA indicates that there were no significant differences between the presence and absence of MnTBAP at each Cr(VI) concentration (p > 0.05).