Table 2. Summary of the statistical analysis of the effects of DVC inactivation and LPS challenge on c-Fos expression in selected brain regions (2-way ANOVA)*.
| Brain region | main effects DVC bupivacaine | LPS treatment | Interaction LPS × DVC Bupiv | |||
|---|---|---|---|---|---|---|
| F(1,13) | p | F(1,13) | p | F(1,13) | p | |
| (behavior related)** | ||||||
| CPu dm | 16.3 | 0.0014 | 9.18 | 0.0097 | 23.86 | 0.0003 |
| HPC d | 7.26 | 0.018 | 4.87 | 0.046 | 4.79 | 0.0474 |
| VTA r | 13.9 | 0.0026 | 1.67 | 0.22 | 9.64 | 0.0084 |
| (LPS-responsive) | ||||||
| PVN | 4.76 | 0.048 | 18.41 | 0.0009 | 7.52 | 0.017 |
| BSTov | 6.34 | 0.026 | 26.44 | 0.0002 | 2.03 | 0.17 |
| CEA | 1.06 | 0.32 | 39.8 | <.0001 | 5.85 | 0.031 |
| PB el | 4.58 | 0.052 | 56.21 | <.0001 | 17.16 | 0.0012 |
| VLM DBH cells | 6.13 | 0.028 | 23.92 | 0.0003 | 5.74 | 0.032 |
significant effects (p < .05) are bolded. Statistics was performed on the total number of c-Fos-immunreactive profiles in each brain region, except for the DBH-labeled neurons in the VLM, which involved the percentage of the total number of DBH cells that expressed c-Fos.
c-Fos expression in the TMV: see Gaykema et al., 2008.