Table 1.
Obsessive–compulsive clinical features in subjects with OCDa in the OCD Collaborative Genetics Study sample
| Number of subjects with OCD | 706 |
| Gender, n (%) | |
| Men | 249 (35) |
| Women | 457 (65) |
| Age at interview (years), mean (range) | 36.3 (7–96) |
| Age at onset of OC symptomsb (years), mean (range) | 10.5 (5–70) |
| Co-morbid disorders, n (%) | |
| Generalized anxiety disorder (GAD) | 289 (43.1) |
| Separation anxiety disorder (SAD) | 161 (24.7) |
| Panic disorder (PD) | 132 (19.2) |
| Tics | 176 (26.2) |
| Major depressive disorder (MDD) | 243 (37.7) |
| Bipolar disorder, mania (Mania) | 47 (6.8) |
| Grooming disorders (GrD) | 256 (39.3) |
| Somatic disorders (Som) | 148 (23.0) |
| Obsessive–compulsive personality disorder (OCPD) | 91 (16.4) |
| YBOCS severity scorec, mean (range) | 24.4 (3–40) |
| OCD factor scoresd, mean (range) | |
| Taboo thoughts | 2.44 (0–14) |
| Symmetry/ordering | 2.31 (0–7) |
| Hoarding | 0.66 (0–2) |
| Doubt/checking | 2.27 (0–12) |
| Contamination/cleaning | 2.76 (0–13) |
| NEO-PI-R factor scorese, mean (range) | |
| Neuroticism | 62.4 (25.8–97.6) |
| Extraversion | 46.3 (9.62–81.4) |
| Openness | 51.8 (19.8–86.0) |
| Agreeableness | 48.6 (–2.33 to 87.2) |
| Conscientiousness | 45.5 (8.85–77.8) |
| Ever treated for OCD symptoms, n (%) of subjects | 489 (73) |
OCD, Obsessive–compulsive disorder; YBOCS, Yale–Brown Obsessive–Compulsive Scale; NEO-PI-R, Revised NEO Personality Inventory.
a
Definite and probable OCD.
b
Age at onset of obsessive–compulsive symptoms.
c
Worst-ever episode.
d
Unit-based scores.
e
NEO-PI-R T scores: average scores in the population are 50 (S.D.=10).