Figure 7.

A) Percent increase from baseline in total input flow (black) (± SEM) compared to model-derived percent increase from baseline in total arteriolar conductance (gray), calculated from the model depicted in Figure 1B. Total arteriolar conductance, estimated from measured 1^st-5^th order arteriolar radii (Figure 2A), exhibits a biphasic response like the biphasic flow response (BFR). B) Calculated conductance of only the 5^th order vessels (black) exhibits a similar biphasic response as the total network conductance (grey). Calculated total network conductance of vessel orders 1-4 (i.e., total conductance with 5^th order vessels removed) do not show a biphasic response. Fifth order changes in conductance are thus both necessary and sufficient for the biphasic flow response to local heat.