Fig. 5.

Percentage of different patterns of fibrillin deposition. (A) Blood and (B) lymphatic human dermal microvascular endothelial cells (HDMECs) at confluence and at days 2 and 4 after confluence. Overall, in blood HDMECs (A), there is a decrease of the simplest Pattern A and an increase of the more complex ones (Patterns B, C and D) with time in culture. In lymphatic HDMECs (B), Pattern A prevails at confluence and decreases at day 2; Patterns B and C increase linearly with time; and Pattern D, absent at confluence, is 6.1% at day 4. Pattern α decreases gradually with time, whereas Pattern β decreases mainly from day 2 to day 4.