Table 1.
Morphometric evaluation of fibrillin deposition by blood and lymphatic human dermal microvascular endothelial cells (HDMECs) in the different patterns.
| HDMECs | Optical density per field | Fiber length (μm) per field | Branching points per field | |||
|---|---|---|---|---|---|---|
| Blood | ||||||
| Pattern A | 11.69 | ± 0.22 | 45 | (40–51) | 30 | (20–43) |
| Pattern B | 13.01 | ± 0.23 | 74 | (67–83) | 67 | (57–79) |
| Pattern C | 14.25 | ± 0.23 | 122 | (107–138) | 131 | (109–158) |
| Pattern D | 14.88 | ± 0.1 | 174 | (159–190) | 261 | (203–335) |
| Lymphatic | ||||||
| Pattern A | 12.1 | ± 0.14 | 21 | (17–26) | 15 | (11–19) |
| Pattern B | 13.07 | ± 0.12 | 40 | (36–45) | 37 | (30–44) |
| Pattern C | 14.42 | ± 0.15 | 95 | (84–108) | 147 | (125–174) |
| Pattern D | 14.76 | ± 0.13 | 187 | (173–202) | 388 | (316–476) |
| Pattern α | 13.13 | ± 0.11 | 12 | (10–15) | ||
| Pattern β | 13.28 | ± 0.07 | 29 | (26–32) | ||
Geometric mean ± SE for optical density, geometric mean with 95% confidence interval in parenthesis for fiber length and branching points. Fiber length and branching points increase from Pattern A to D in both blood and lymphatic HDMECs. Mean fiber length is smaller in lymphatic than in blood HDMECs except for Pattern D. No branching points were detected in Patterns α and β.