Table 2.
Capillary supply and indices of cellular proliferation
| C:F | CD (mm−2) | PCNAcap (mm−2) | PCNAint (mm−2) | PCNAmyo (mm−2) | |
|---|---|---|---|---|---|
| Control (8) | 1.40 ± 0.09 | 827 ± 79 | 9.2 ± 2.1 | 5.4 ± 1.2 | 3.1 ± 0.8 |
| 4d Lig (4) | 1.49 ± 0.05 | 835 ± 19 | 11.2 ± 4.2 | 5.8 ± 0.4 | 12.3 ± 3.1 |
| 7d Lig (7) | 1.50 ± 0.06 | 853 ± 46 | 9.6 ± 4.9 | 9.6 ± 1.9 | 8.5 ± 3.0 |
| 14d Lig (4) | 1.47 ± 0.06 | 774 ± 34 | 8.1 ± 1.5 | 8.1 ± 1.9 | 5.6 ± 1.4 |
| 4d Ten(4) | 1.37 ± 0.05 | 875 ± 47 | 18.7 ± 4.6 | 18.9 ± 4.9 | 15.1 ± 9.4 |
| 7d Ten(7) | 1.46 ± 0.05 | 843 ± 38 | 19.4 ± 3.4 | 18.8 ± 4.2 | 8.6 ± 2.4 |
| 14d Ten (4) | 1.52 ± 0.02 | 869 ± 54 | 38.4 ± 5.9* | 36.2 ± 7.5** | 5.9 ± 1.0 |
| 4d Ext (4) | 1.47 ± 0.04 | 844 ± 28 | 20.1 ± 5.0 | 19.2 ± 6.5 | 18.9 ± 4.4* |
| 7d Ext (7) | 1.40 ± 0.05 | 949 ± 51 | 62.4 ± 7.3** | 62.7 ± 13.1** | 33.6 ± 8.7** |
| 14d Ext (4) | 2.11 ± 0.07** | 1038 ± 60* | 16.1 ± 3.6 | 16.5 ± 3.2 | 18.3 ± 6.2* |
Means ± s.e.m. (number of animals).
*
P < 0.05
**
P < 0.001 vs. Control.
Abbreviations: C:F, capillary to fibre ratio; CD, capillary density; PCNA, profiling cell nuclear antigen; caps, capillaries; int, interstitium; myo, myonuclear.