Figure 3.
Recovery of NE and the effects of hydrolase inhibitor, OTFP, on proliferation in LNCaP cells. (A) Recovered NE in LNCaP cells in the absence and presence of OTFP (10 μM) at 0-h and 2-h incubation. The amount of added NE was 18.25 μg. Values are mean ± SD (n = 3). *, significantly lower than the control cells with p < 0.05. (B) Proliferation (thymidine incorporation assay) of LNCaP cells treated with NE (10 μM), OFTP (10 μM), and a combination of NE and OTFP. Values are mean ± SEM (n = 12-18). *, significantly lower than the control cells with p < 0.05; **, significantly lower than each treatment alone with p < 0.05.