TABLE 2.
Electrophoretic mobility of Kv2.1, Kv4.2, and Kv4.3 ± sialidase and O-glycanase treatments
Data are the mean Mr ± S.E. for Kv2.1, Kv4.2, and Kv4.3 whole Pro5 cell lysates. Significance was tested using a two-tailed Student's t-test to compare untreated controls with treated lysates. * indicates significance (p < 0.005), or between treated lysates, # indicates significance (p < 0.05).
| Isoform | n | Untreated control | Sialidase-treated | O-Glycanase-treated |
|---|---|---|---|---|
| kDa | kDa | kDa | ||
| Kv2.1 | 6 | 105.2 ± 0.5 | 101.0 ± 0.6* | 98.9 ± 0.4*# |
| Kv4.2 | 4 | 65.6 ± 0.1 | 63.4 ± 0.5* | 61.6 ± 0.5*# |
| Kv4.3 | 8 | 69.0 ± 0.8 | 66.5 ± 0.7* | 64.2 ± 0.8*# |