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Association of active histone marks with the promoter, Up GAA, and Down GAA region of the frataxin gene in unaffected (GM06865) and FRDA cells (GM15850, GM16243, GM16209, and GM04079). A, schematic representation of the FXN gene showing the positions of the regions analyzed by real-time PCR in ChIP assays. B, chromatin immunoprecipitated with indicated antibodies was normalized to 5% of input and expressed relative to GAPDH. Error bars indicate S.D.
