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G6 decreases the percentage of blast cells in the peripheral blood and reduces the spleen weight to body weight ratio in a mouse model of Jak2-V617F-mediated hyperplasia. A, percentages of blast cells in the peripheral blood plotted as a function of both treatment group and days of treatment. *, p < 1.0 × 10−4 versus DMSO-treated mice. B, spleen to body weight ratio was obtained and plotted as a function of treatment group. #, p < 0.05 versus naïve mice; *, p < 0.05 versus HEL+DMSO.
