TABLE 3.
Amino acid sequence alignment of 70–80 and 140–155 loops (chymotrypsin numbering) of Pm and selected serine proteases surrounding the S2′ subsite pocket
Residues 73 and 143 are shaded and are acidic in Pm as compared with the other serine proteases involved in blood coagulation. To aid the reader in identifying the 70–80 and 140–150 segment positions in each protease, the actual sequence numbers (where available) are also given in braces following the name of the protease.