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. 2010 Dec 3;286(6):4566–4575. doi: 10.1074/jbc.M110.199976

FIGURE 9.

FIGURE 9.

Heat stress selectively impairs DNA integrity in Tau-deficient neuronal cultures. The effect of HS on DNA from wild-type (Tau+/+) or Tau-deficient cells (Tau−/−) was measured by Comet assay. Results are presented as the OTM ratio from heat-shocked cells (HS) over control (C). Each OTM value is a median value from 150 to 200 cells. Data shown are the means from three different experiments using separate cultures. **, p < 0.01.