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. 2010 Oct 6;1(6):405–422. doi: 10.18632/oncotarget.175

Table 1. List of the top differentially regulated genes between both of the LFS and WT cells in epithelial and stromal tissue types.

Gene Symbol Description Fold Change p-value
Genes upregulated in LFS vs. WT epithelial cells
ZNF415 Zinc finger protein 415 10.411 5.96E-05
BIRC3 Baculoviral IAP repeat-containing 3 9.628 3.13E-03
NMES1 Normal mucosa of esophagus specific 1 9.509 1.43E-02
Transcribed locus 9.431 1.35E-04
DNCI2 Dynein, cytoplasmic, intermediate polypeptide 2 7.322 5.94E-07
EGR3 Early growth response 3 7.059 5.23E-03
GPNMB Glycoprotein (transmembrane) nmb 7.044 5.80E-04
ZNF506 zinc finger protein 506 7.005 8.66E-10
MICB MHC class I polypeptide-related sequence B 6.998 1.23E-04
EMP2 epithelial membrane protein 2 6.809 6.28E-03
Genes downregulated in LFS vs. WT epithelial cells
MYEF2 Myelin expression factor 2 −7.196 8.10E-06
DOC1 Downregulated in ovarian cancer 1 −8.229 1.25E-05
C7orf10 Chromosome 7 open reading frame 10 −10.124 1.86E-08
C13orf18 Chromosome 13 open reading frame 18 −10.519 6.49E-07
GHR Growth hormone receptor −11.471 7.45E-11
HOXB7 Homeo −14.978 7.37E-08
ANGPTL4 Angiopoietin-like 4 −18.426 1.81E-09
SLC38A5 Solute carrier family 38, member 5 −18.469 2.92E-04
NEFL Neurofilament, light polypeptide 68kDa −19.512 8.72E-06
XG Xg blood group (pseudoautosomal boundary-divided on the X chromosome) −65.958 7.36E-05
Genes upregulated in LFS vs. WT stromal cells
TM4SF1 Transmembrane 4 superfamily member 1 31.899 1.27E-05
TM4SF1 Transmembrane 4 superfamily member 1 29.644 5.12E-06
TM4SF1 Transmembrane 4 superfamily member 1 25.646 2.62E-05
TM4SF13 Transmembrane 4 superfamily member 13 12.675 2.54E-04
FABP5 Fatty acid binding protein 5 (psoriasis-associated) 10.582 3.50E-03
G0S2 Putative lymphocyte G0/G1 switch gene 10.572 3.60E-03
PTGS1 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 9.926 1.67E-05
RAMP RA-regulated nuclear matrix-associated protein 9.155 1.13E-04
RAD51AP1 RAD51 associated protein 1 9.132 9.19E-03
FLJ31340 Hypothetical protein FLJ31340 9.020 2.03E-02
Genes downregulated in LFS vs. WT stromal cells
ARHGAP26 Rho GTPase activating protein 26 −6.532 6.63E-08
CCND2 Cyclin D2 −6.615 1.17E-02
RGC32 Response gene to complement 32 −7.036 2.60E-16
PSG4 Pregnancy specific beta-1-glycoprotein 4 −7.149 1.09E-15
Transcribed locus −7.179 4.97E-10
RDH10 Retinol dehydrogenase 10 (all-trans) −7.779 8.74E-12
STEAP2 Six transmembrane epithelial antigen of prostate 2 −8.158 1.67E-21
COPl CARD only protein −10.944 2.92E-08
GPM6B Glycoprotein M6B −11.299 8.01E-06
GPM6B Glycoprotein M6B −11.772 1.42E-06