| Epithelial Cells |
| Wnt/β-catenin Signaling |
CSNK1E,CDKN2A,CSNK1G1,PPP2R2B,TGFB2,PPP2R2C,KREMEN1,DKK1,CTNNB1,EP300 |
| Tight Junction Signaling |
MYLK,MPDZ,CLDN12,PPP2R2B,PVRL3,TGFB2,PPP2R2C,ACTG2 (includes EG:72),CTNNB1 |
| Cycle: G1/S Checkpoint Regulation |
CDKN2A,CCND2,NRG1,CDK6,TGFB2 |
| Aryl Hydrocarbon Receptor Signaling |
CDKN2A,CCND2,ALDH1A3,NQO1,CDK6,TGFB2,IL1B,EP300 |
| Coagulation System |
PROS1,SERPINA1,PLAU,F3 |
| NRF2-mediated Oxidative Stress Response |
FTL,NQO1,DNAJC1,AOX1,ACTG2 (includes EG:72),FKBP5,TXNRD1,EP300,EPHX1 |
| p53 Signaling |
CDKN2A,CCND2,THBS1,C12ORF5,CTNNB1,EP300 |
| Acute Phase Response Signaling |
FTL,FN1,IL1RN,IL1B,C5,SERPINA1,STAT3,IL1RAP |
| Selenoamino Acid Metabolism |
SEPHS1,GGT1,AHCY |
| Eicosanoid Signaling |
AKR1C3,PNPLA3,PTGS2,GGT1 |
| Stromal Cells |
| Aryl Hydrocarbon Receptor Signaling |
TP53,GSTM1,CCNE2,POLA1,GSTM3 (includes EG:2947),NQO1,BAX,CHEK1,CCNA2,GSTM2,CCND2,ALDH1A3,CDKN1A,GSTM4,IL1B,DHFR,CDK2,MCM7 |
| Role of BRCA1 in DNA Damage Response |
TP53,RAD51,RFC4,MSH2,CDKN1A,MSH6,RFC2,RBL1,RFC5,CHEK1 |
| Pyrimidine Metabolism |
TYMS,PRIM1,NME5,DCK,POLE2,POLA1,RRM2B,RRM2,REV3L,RFC5,CTPS,NME7,RRM1,POLD3,NP,POLA2,TK1 |
| p53 Signaling |
TP53,CCNG1,GADD45B,CCND2,RRM2B,CDKN1A,TNFRSF10B,BAX,CDK2,BIRC5,CHEK1,DRAM (includes EG:55332) |
| Cycle: G1/S Checkpoint Regulation |
TP53,CCNE2,CCND2,HDAC8,SUV39H1,CDKN1A,NRG1,RBL1,CDK2 |
| Glutathione Metabolism |
GPX3,GSTM1,TRHDE,GSTM2,GSTM3 (includes EG:2947),GPX1,GSTM4,G6PD,H6PD,GCLM |
| Purine Metabolism |
PRIM1,ATP1B1,NME5,DCK,DDX39,POLE2,POLA1,RRM2B,RRM2,REV3L,RFC5,NME7,RRM1,RAD51,PRPS2,POLD3,PRPS1,NP,ADA,POLA2,PDE5A,ENPP2,AOX1,PPAT |
| Pentose Phosphate Pathway |
PRPS2,PRPS1,TKT,G6PD,H6PD,ALDOC |
| NRF2-mediated Oxidative Stress Response |
GSTM1,DNAJC9,GSTM3 (includes EG:2947),NQO1,GSTM2,RRAS2,SOD2,CAT,GSTM4,SQSTM1,AOX1,GCLM,ACTC1,PRKD1,FTH1 |
| Histidine Metabolism |
PRPS2,PRPS1,ALDH1A3,FTSJ1,MAOA |
