. Author manuscript; available in PMC: 2011 Feb 15.

Published in final edited form as: Mol Biochem Parasitol. 2008 Dec 25;164(2):111–117. doi: 10.1016/j.molbiopara.2008.12.007

Table 3.

Effect of paromomycin (PR) on mitochondrial and cytoplasmic protein synthesis in promastigotes of wild-type and paromomycin-resistant Leishmania donovani

Treatment	Wild-type	PRr
Untreated control	100	100
PR (1 mM)	79 ± 3.5	98 ± 2.1
Cycloheximide (70 µM)	51 ± 3.5	38 ± 11.3
PR + Cycloheximide	29 ± 9.8	42 ± 12.7
Chloramphenicol (1 mM)	59 ± 5.7	66 ± 5.6
PR + Chloramphenicol	29 ± 1.4	66 ± 2.1

Cells were treated as described in materials and methods. Results are expressed as percentage incorporation of isoleucine in treated cells in comparison to the untreated controls. Data represents mean ± SD of duplicate values from two independent experiments.