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. 2010 Aug 18;19(1):112–114. doi: 10.1038/ejhg.2010.127

Table 2. Reported variations of type II familial synpolydactyly in the literature.

Authors Variations
Cross et al3 Some hands show the third web syndactyly without any polydactyly, and the feet may be normal
Camera et al2 Aplasia/hypoplasia of middle phalanges of the toes
Merlob and Grunebaum6 Metacarpal/metatarsal abnormalities such as ‘widening', ‘narrowing' or ‘Y-shaped'
Sayli et al10 Simultaneous pre- and postaxial polydactyly, concurrent postaxial polydactyly type A, bilateral little finger clinodactyly, hypoplasia of the middle phalanges
Temtamy and McKusick11 Concurrent clinodactyly of the little fingers
Kjaer et al5; De Smet4 Concurrent clinodactyly of the little finger. Some family members show isolated clinodactyly indicating that the gene may be expressed as an isolated clinodactyly
Ridler et al8 Some family members show isolated little finger minor abnormalities such as camptodactyly, hypoplasia/aplasia of the distal phalanx. Distortion of dermatoglyphic patterns may be seen in severe cases
Akarsu et al1 (homozygous phenotype) Synpolydactyly may involve all digits, short hands and feet, some of the metatarsals/metacarpals lose their normal tubular shape and appear polygonal, tarsometatarsal fusions, phalangeal synostosis
Muragaki et al7 (homozygous phenotype) Syndactyly includes the third and fourth web spaces, severe brachydactyly, affecting all digits, some of the metatarsals/metacarpals lose their normal tubular shape and appear very short and frequently there are accessory carpal bones