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. 2010 Aug 18;19(1):108–111. doi: 10.1038/ejhg.2010.139

Table 3. Genetic model-fitting results for cervical smear.

  Model 2LL df vs χ2 Δdf P AIC a2 c2 e2
1 Full ACE 2302.350 2688         −3073.650 0.37 2.6−10 0.63
2 E model 2315.051 2690 1 12.701 2 0.002 −3064.949 1.00
3 CE model 2304.188 2689 1 1.838 1 0.175 −3073.812 0.23 0.77
4 AE model 2302.350 2689 1 0 1 1.000 3075.650 0.37 0.63

Abbreviations: −2LL, −2 log likelihood; χ2, by substracting the −2LL of two different (nested) models yields a statistic that is asymptotically distributed as χ2distribution; AIC, Akaike's Information Criterion: a lower value of AIC indicates a more parsimonious model; df, degrees of freedom; Δdf, difference in degrees of freedom between two models; P, P-value; vs, tested versus model.

Cervical smear results were categorized in no abnormalities, mild abnormalities and severe abnormalities. Thresholds (=prevalences) were allowed to vary with age group (<40 or ≥40 years) and year of diagnosis (<1996 or ≥1996). a2, additive genetic influences; c2, common environmental influences; e2, unique environmental factors.