Table 1.
Summary of Spearman's correlation coefficients between FST and ϕ as the discordance in replicabilities for the 37 associations from the Continental Set
| ASSOCIATIONS | CATHEGORY | POOLINGa | VARIABLEb | N | P value | |
|---|---|---|---|---|---|---|
| Full Set | All SNPs | By Gene | Average FST | 33 | 0.496 * | 0.003 |
| Variance FST | 32 | 0.636 * | 7 × 10-5 | |||
| Independently | Average FST | 3710 | 0.155 * | 2.58 × 10-21 | ||
| tagSNPs | By Gene | Average FST | 33 | 0.187 | 0.313 | |
| Independently | Average FST | 538 | 0.16 * | 2.02 × 10-4 | ||
| Conservative Setc | All SNPs | By Gene | Average FST | 26 | 0.666 * | 0.0002 |
| Variance FST | 24 | 0.666 * | 4.5 × 10-6 | |||
| Independently | Average FST | 2454 | 0.15 * | 0.628 | ||
| tagSNPs | By Gene | Average FST | 24 | 0.453 | 0.280 | |
| Independently | Average FST | 486 | 0.063 * | 6.85 × 10-4 | ||
a Pooling by gene tests average genic FST, while in pooling independently each SNP has been assigned the replicability from the association it belongs to
b Variable indicates which parameter (either average or variance in FST) has been tested versus ϕ
c Conservative set contains those associations that have a replicability of ≥50% in at least one continent