Skip to main content
. 2011 Feb 15;6(2):e17083. doi: 10.1371/journal.pone.0017083

Table 1. Common transcription factor binding sites in the 9-gene signature.

Best hit Weight Matrix consensus Transfac ID Factor name
GCACCTG 6.5 ASCACCTGTTNNCA M00044 Snail*
CAGGTGC 6.5 RACAGGTGYA M00060 Snail*
GCACCTG 6.5 VNRCACCTGKNC M00414 AREB6/ZEB1*
CAGGTGC 6.21 CNNCAGGTGB M00277 LMO2 complex*
CAGGTGC 6 RRCAGGTGNCV M00693 E12/ELSPBP1*
CAGGTGC 6 CNGNRNCAGGTGNNGNA M00929 MyoD*
GCACCTG 5.5 YNYACCTGWVT M00412 AREB6/ZEB1*
GCACCTG 4 RRTGNMCYTNNTGAMCCNYNT M00966 VDR, CAR, PXR
GCACCTG 3.5 GCTGGNTNGNNCYNG M00947 CP2/LBP-1c/LSF
GCACCTG 3.5 RGNACNNKNTGTTCT M00957 PR/Progesterone receptor
GCACCTG 3.5 TGGCASNNNGCCAA M01196 CTF1

A list of binding sites matching to best 7-mer found in promoters of the common EMT gene signature. Three muscle initiator sequences with no further information were excluded.

*E-box binding transcription factors. E12 is part of the LMO2 complex.