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. 2011 Feb 15;6(2):e16959. doi: 10.1371/journal.pone.0016959

Figure 5. Deletion of COX-1 mimics the effects of ASA on parasitemia but not survival in T. cruzi infected mice.

Figure 5

A and B . Survival curves (A) and peripheral parasitemia (B) for WT (black circle), TXA2 synthase null mice (grey circle) and COX1 null mice (○) mice after inoculation with 105 trypomastigotes of the Brazil strain. C and D . Measurement of plasma PGF2α (C) and TXB2 (D) in infected WT (black square), TXA2 synthase null mice (grey square) and COX-1 null mice (white square) mice. Data are represented as mean ± SD are representative of at least 20 mice per group. * and # indicates significance (P≤0.05) from uninfected and infected WT mice, respectively.