Figure 6. Treatment of T. cruzi-infected mice with ASA modulates cytokine signaling in the spleen of infected mice.

Splenic extracts were prepared from uninfected and infected CD1 mice treated with ASA (20 mg/kg) from 5 dpi. Immunoblotting for TNF-α, SOCS-2 and TRAF-6 was performed on 15 and 30 dpi. β-actin was used as a loading control. Immunoblots are representative from at least three separate experiments.