Table 5. Therapeutic category of anti-leishmanial compounds identified in the ex vivo splenic explant system.
Anti-protozoa | Anti-bacterial | Anti-helmintic |
Elipticine | Nonactin | Pararosaniline Pamoate |
Nigericin | Aklavine Hydrochloride | Naphthofuran d |
Cepharanthine | Nigericin | Cetrimonium Bromide |
Disulfiram | Naphthofuran d | Disulfiram |
Tilorone | Streptovitacin A | |
3-phenanthren a | 5-methyl-8-quinolinol c | Anti-fungal |
Benzalkonium Chloride | Securinine | Pararosaniline Pamoate |
Physalin | Cepharanthine | Naphthofuran d |
Chlorhexidine | Parthenicin | Cetrimonium Bromide |
Cloxyquin | Disulfiram | Disulfiram |
Tetrandrine | Salinomycin, Sodium | Acrisorcin |
Clioquinol | Rubescensin A | Benzalkonium Chloride |
Hexachlorophene | 7-hydroxychlorpromazine | Clioquinol |
Lasalocid Sodium | Lasalocid Sodium | Hexachlorophene |
Lasalocid Sodium | ||
Anti-neoplastic | Topical/Antiseptics | Antimycin A |
Aklavine Hydrochloride | 5-methyl-8-quinolinol c | 5-methyl-8-quinolinol c |
Thaspine, Acetate | Cetrimonium bromide | |
Ellipticine | Benzalkonium chloride | Immune response regulator |
NSC 134754 | Chlorhexidine | n6-Isopentenyladenine |
Streptovitacin A | Clioquinol | Spermidine Trihydrochloride |
Cepharanthine | Hexachlorophene | NSC 13480 |
Benzethonium Chloride | Cetylpyridinium Chloride | 6,4′-Dimethoxyflavone |
Rubescensin A | NSC 371488 | |
10-Methyl-9-anthracenyl f | Anti-viral | Sumilit bbm |
Tilorone | Nigericin | Securinine |
Crassin | Cepharanthine | Cepharanthine |
Tetrandrine | Trimethoxychalcone g | |
NSC 305819 | Tilorone | Anti-obesity/Anti-psychotics |
NSC 371488 | Benzalkonium Chloride | 1h-benz[de]isoquinoline b |
Clioquinol | Crassin Acetate | Nortriptyline Hydrochloride |
Fastigilin B | Disulfiram | |
Thioxanthen-9 e | Undefined h | Orlistat |
Crassin acetate | Thiomethylpromazine | |
6,4′-dimethoxyflavone | Chlorpromazine | |
7-hydroxychlorpromazine | ||
Maprotiline hydrochloride |
3-phenanthrenemethanol, alpha.-[(diethylamino)methyl]-,hydrochloride.
1h-benz[de]isoquinoline-1,3(2 h)- dione, 5-amino-2-[2-(diethylamino)ethyl]-
7-(2-(6-ethoxy-1-methyl-1lambda(5)-quinolin-2-yl)vinyl)-5-methyl-8-quinolinol.
naphtho(2,1-b)furan, 4 methoxy-2 -nitro-
thioxanthen-9-one, 4-(hydroxymethyl)-1-[(2-piperidinoethyl)amino.
10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride.
2′,4-dihydroxy-3,4′,6′ Trimethoxychalcone.
Undefined activity: pyrimido[4,5-b]quinoline-2,4(3 h,10 h)-dione, 5-[[3-(dimethylamino)propyl]amino]- 3,10-dimethyl-,monohydrochloride]-; 17-(1-((2-(dimethylamino)ethyl)amino)ethyl) estra-1,3,5(10)-trien-3-ol; N1-(7-chloro-1,2,3,4-tetrahydro-9-acridinyl)-N3,N3-dimethyl-1,3-propanediamine; 2-[(2E)-2-hydroxyimino-4,6,6-trimethyl-1-cyclohex-3-enyl]-4,6,6-trimethyl-cyclohex-3-en-1-ol; 3-(12H-benzo[a]phenothiazin-12-yl)-N,N-dimethyl-1-propanamine; 5-Phenyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-5-ol; 7-chloro-N-(4-(1-piperidinyl)cyclohexyl)-4-quinolinamine; 2-(3-dimethylaminopropylamino)-1,4-dihydroxy-anthracene-9,10-dione; 17-(Bis(2-hydroxyethyl)amino)androst- 5-en-3-ol; N1-7-chloro-4-quinolinyl)-N2-cyclohexyl-1,2-ethanediamine; 6-methoxy-N-[2-(2-piperidyl)ethyl]quinolin-8-amine.