Table 2.

Significant molecular and cellular functions associated with the lactosome fraction

Significant Function	Associated Proteins
Lipid Metabolism	APOE, APOB, APOA1, CLU, BTN1A1, LALBA, CEL, ALB, LTF, PLIN2, PSAP, SERPINA1, FABP3
Molecular Transport	B2M, APOE, TTR, APOB, APOA1, CLU, BTN1A1, LALBA, CEL, ALB, LTF, PLIN2, CSN2, PSAP, FABP3
Small Molecule Biochemistry	APOE, GNPDA1, TTR, APOB, APOA1, CLU, LALBA, BTN1A1, LYZ, CEL, ALB, LTF, PLIN2, PSAP, SERPINA1, FABP3, KRT1
Protein Synthesis	APOE, APOB, APOA1, CSN2, LALBA
Cellular Movement	APOE, CD59, SPP1, APOB, CFL1, APOA1, CLU, LIMS1, KRT10, PIGR, ACTG1, ALB, SERPINA1, C4B
Cellular Assembly and Organization	B2M, APOE, CD59, TTR, SPP1, CFL1, APOA1, SEPT7, CLU, MFGE8, KRT9, CST3, PLIN2
Cell Death	PKM2, B2M, APOE, TTR, CD59, APOB, SPP1, CFL1, APOA1, CLU, YWHAZ, LIMS1, LALBA, MFGE8, LYZ, KRT10, PIGR, ALB, CST3, PSAP
Carbohydrate Metabolism	PKM2, CEL, APOE, ALB, GNPDA1, SPP1, APOA1, PSAP, LALBA, LYZ, FABP3
Amino Acid Metabolism	APOE, TTR, ALB
Cell-To-Cell Signaling and Interaction	B2M, APOE, TTR, CD59, SPP1, APOB, CFL1, APOA1, CLU, MFGE8, LIMS1, LYZ, PIGR, ALB, LTF, KRT2, KRT1, C4B
Antigen Presentation	APOE, APOB, SPP1, APOA1, KRT1, PIGR, C4B
Cellular Growth and Proliferation	B2M, APOE, CD59, SPP1, CFL1, TFG, APOA1, CLU, MFGE8, KRT10, MYOF, PIGR, CST3, KRT2, SERPINA1, FABP3, KRT4
Protein Trafficking	APOE, APOA1, CSN2, LALBA
Gene Expression	PIP, SPP1, CLU, YWHAZ, LALBA
Cellular Compromise	APOE, SPP1, CFL1, SEPT7, CLU
Cell Morphology	B2M, APOE, SPP1, LTF, CFL1
Cellular Development	B2M, APOE, CD59, SPP1, CST3, CLU
Cellular Function and Maintenance	KRT9, APOE, CD59, SPP1, CFL1, CST3, CLU
Post-Translational Modification	CEL, APOE, ALB, C4B
Vitamin and Mineral Metabolism	APOE, CEL, APOA1, PLIN2, KRT1