Table 2. Ever/never use and temporality of antidepressant medication use among colorectal cancer cases and matched controls in Northern Denmark, 1991–2008 (number, %).

	Cases		Controls
	N=9979	%	N=99 790	%	OR a	95% CI
Tricyclic antidepressants
Never/rare use	9614	96	95 800	96	1.00
Ever use	365	3.7	3990	4.0	0.94	0.84, 1.05
Temporality of use
Never/rare use	9614	96	95 800	96	1.00
Recent use   (0 to <2 years)	184	1.8	2029	2.0	0.93	0.80, 1.09
Former use   (2+ years)	181	1.8	1961	2.0	0.95	0.81, 1.11
Selective serotonin reuptake inhibitors
Never/rare use	9128	92	90 900	91	1.00
Ever use	851	8.5	8890	8.9	0.97	0.90, 1.05
Temporality of use
Never/rare use	9128	92	90 900	91	1.00
Recent use   (1 to <2 years)	540	5.4	6693	6.7	0.97	0.88, 1.07
Former use   (2+ years)	311	3.1	2197	2.2	0.97	0.86, 1.09
Other antidepressants
Never/rare use	9689	97	96 654	97	1.00
Ever use	290	2.9	3136	3.1	0.95	0.83, 1.07
Temporality of use
Never/rare use	9689	97	96 654	91	1.00
Recent use   (1 to <2 years)	188	1.9	2007	2.0	0.96	0.83, 1.12
Former use   (2+years)	102	1.0	1129	1.1	0.92	0.75, 1.13

Abbreviations: CI=confidence interval; NSAIDs=non-steroidal anti-inflammatory drugs; OR=odds ratio.

^aAdjusted for diabetes, alcoholism, inflammatory bowel disease, use of NSAIDs, use of statins, use of hormone replacement therapy, use of aspirin, use of neuroleptics, and marital status.