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. 2011 Feb 14;208(2):395–407. doi: 10.1084/jem.20100466

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© 2011 Okazaki et al.

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Figure 6. — Gastritis in BALB/c-Pdcd1^−/− mice requires autoAbs that have undergone SHM and/or CSR. (A) Incidence of gastritis of indicated grade (0, 1, 2, and 3) at 21–23 wk of age in BALB/c-Pdcd1^−/− (n = 10), BALB/c-Aicda^−/−Pdcd1^−/− (n = 7), BALB/c-Aicda^−/−Lag3^aida/aida (n = 9), BALB/c-Aicda^−/− (n = 6), BALB/c-Lag3^aida/aida (n = 6), and BALB/c wild-type (n = 5) mice. (B) Representative histology of the stomach of BALB/c-Pdcd1^−/− and BALB/c-Pdcd1^−/−Aicda^−/− mice.