Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Feb 14;208(2):217–225. doi: 10.1084/jem.20100370

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 de Jager et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — GDF-15 is progressively expressed in atherosclerotic lesions in a pattern similar to that of macrophages. (A–D) Temporal expression of GDF-15 (A), CD68 (B), Smoothelin (C) and PECAM-1 (D) during atherogenesis was assessed by whole genome microarray. Values are expressed as fold induction compared with time point zero. The experiment was performed twice, with n = 3 (each containing pooled plaque material of three mice) per time point. *, P < 0.05; ***, P < 0.001, compared with the 0-wk timepoint. Error bars are depicted as SEM. (E and F) Immunohistochemistry for GDF-15 in human (E) and murine (F) atherosclerotic lesions. Arrows represent intimal cells (based on nuclear staining) that express GDF-15.