Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Feb 14;208(2):261–271. doi: 10.1084/jem.20101688

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 Chow et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 5. — Depletion of BM CD169⁺ MΦ, but not CD169⁻ MOs, mobilizes HSCs/progenitors. (A–D) Wild-type (WT) or heterozygous CD169-DTR (CD169^DTR/+) mice were treated with DT. (A) Representative dot plots show the percentages of BM mononuclear phagocytes in wild-type (top) or CD169^DTR/+ mice treated with DT (bottom). (B–D) Bar graphs depict the absolute numbers of mononuclear phagocytes (n = 6) in wild type mice and wild type or CD169^DTR/+ mice injected with DT. (E–F) Bar graphs enumerate Lineage⁻ Sca-1⁺ c-kit⁺ (LSK; E) and LSKFlk2⁻cells (F) per milliliter of blood in the same mice analyzed in B–D (n = 6). Data are pooled from two independent experiments. (G) CXCL12 levels were measured 72 h after administration of PBS or 1 µg/ml DT into Dexter cultures plated from the BM of CD169-DTR animals (n = 3–4 wells). Representative data from two independent experiments are shown.

HHS Vulnerability Disclosure