Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Feb 14;208(2):273–284. doi: 10.1084/jem.20101643

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 Takizawa et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 4. — Maintenance of biologically defined HSCs over time and steady-state serial transplantation revealing changing divisional frequencies of LKS. (A) Mathematically calculated mean number of 0×- or ≥5×-divided biologically defined HSCs per mouse over time based on engraftment data described in Materials and methods and Table S2. (B) Experimental scheme of steady-state serial transplantation of cycling LKS cells into nonirradiated mice. (C) Representative dot plots of BM from secondary transplants gated on donor (CD45.2⁺) or host (CD45.1/2⁺) Lin⁻ cells at 6 wk after secondary transplantation. Dashed lines represent zero division.