Figure 3.

Polarity switching by the Ras-like GTPase MglA (green oval) and its GTPase-activating protein (GAP) MglB (red oval) in gliding Myxococcus xanthus cells. (A) A time series of gliding M. xanthus cells expressing MglA-YFP and MglB-mCherry that were imaged every 20 seconds by fluorescence microscopy (by Yong Zhang and Tâm Mignot). The yellow coloring indicates the colocalized MglA and MglB. The white arrow indicates the direction of movement that reverses during the course of the experiment. (B) A schematic of the cells and polarly localized proteins from panel A. The straight lines denote the pili that confer S-motility.